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Wiley, Angewandte Chemie International Edition, 8(52), p. 2318-2322, 2013

DOI: 10.1002/anie.201208840

Wiley, Angewandte Chemie, 8(125), p. 2374-2378, 2013

DOI: 10.1002/ange.201208840

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PH-responsive nutraceutical-mesoporous silica nanoconjugates with enhanced colloidal stability

Journal article published in 2013 by Rémy Guillet-Nicolas ORCID, Amirali Popat, Jean-Luc Bridot, Gregory Monteith ORCID, Shi Zhang Qiao, Freddy Kleitz
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

An innovative platform for targeted oral drug delivery is proposed based on the functionalization of drug/dye-loaded mesoporous silica nanoparticles (MSNs) with a biodegradable nutraceutical (β-lactoglobulin). The attachment of the nutraceutical not only protects the drug/dye from leaching in acidic environment, but also effectively allows their release in desired basic sites (pH 7.4). ; Rémy Guillet-Nicolas, Amirali Popat, Jean-Luc Bridot, Gregory Monteith, Shi Zhang Qiao, and Freddy Kleitz