AbstractOxide glasses are an elementary group of materials in modern society, but brittleness limits their wider usability at room temperature. As an exception to the rule, amorphous aluminum oxide (a‐Al₂O₃) is a rare diatomic glassy material exhibiting significant nanoscale plasticity at room temperature. Here, it is shown experimentally that the room temperature plasticity of a‐Al₂O₃ extends to the microscale and high strain rates using in situ micropillar compression. All tested a‐Al₂O₃ micropillars deform without fracture at up to 50% strain via a combined mechanism of viscous creep and shear band slip propagation. Large‐scale molecular dynamics simulations align with the main experimental observations and verify the plasticity mechanism at the atomic scale. The experimental strain rates reach magnitudes typical for impact loading scenarios, such as hammer forging, with strain rates up to the order of 1 000 s⁻¹, and the total a‐Al₂O₃ sample volume exhibiting significant low‐temperature plasticity without fracture is expanded by 5 orders of magnitude from previous observations. The discovery is consistent with the theoretical prediction that the plasticity observed in a‐Al₂O₃ can extend to macroscopic bulk scale and suggests that amorphous oxides show significant potential to be used as light, high‐strength, and damage‐tolerant engineering materials.