Chip-scale multimode optomechanical systems have unique benefits for sensing, metrology, and quantum technologies relative to their single-mode counterparts. Slot-mode optomechanical crystals enable sideband resolution and large optomechanical couplings of a single optical cavity to two microwave-frequency mechanical modes. Still, previous implementations have been limited to nanobeam geometries, whose effective quantum cooperativity at ultralow temperatures is limited by their low thermal conductance. In this work, we design and experimentally demonstrate a two-dimensional mechanical–optical–mechanical (MOM) platform that dispersively couples a slow-light slot-guided photonic-crystal waveguide mode and two slow-sound ∼ 7 GHz phononic wire modes localized in physically distinct regions. We first demonstrate optomechanical interactions in long waveguide sections, unveiling acoustic group velocities below 800 m/s, and then move on to mode-gap adiabatic heterostructure cavities with a tailored mechanical frequency difference. Through optomechanical spectroscopy, we demonstrate optical quality factors Q ∼ 105, vacuum optomechanical coupling rates, go/2π, of 1.5 MHz, and dynamical back-action effects beyond the single-mode picture. At a larger power and adequate laser-cavity detuning, we demonstrate regenerative optomechanical oscillations involving a single mechanical mode, extending to both mechanical modes through modulation of the input laser drive at their frequency difference. This work constitutes an important advance toward engineering MOM systems with nearly degenerate mechanical modes as part of hybrid multipartite quantum systems.