Abstract The dynamics of the mountain vegetation is governed by multiple climatic drivers including temperature, precipitation, radiation and snow cover variability. However, in the Mediterranean environment, little is known about the relative importance of each variable. In this study we assess how different snowpack indices (the maximum annual accumulation, the length of the snow season, and the melt-out date) and key climate variables (precipitation, temperature and shortwave solar radiation) control the interannual variability of the maximum Normalized Difference Vegetation Index (peak NDVI) in the Pyrenees. We use a 33 year long remote sensing dataset (1981–2014) to build a statistical model relating the annual peak NDVI with snow and climate variables. In elevated areas characterized by a well developed seasonal snowpack the melt-out date was the most important climatic variable for predicting the annual peak NDVI. However, at lower elevations where snow presence is ephemeral, shortwave solar radiation was the most important variable. This change in the relative importance of climatic variables occurs around 1300 m a.s.l. The results do not show a significant contribution of maximum snow accumulation, suggesting that indicators of snow presence (i.e. melt-out date or snow season duration), which are significantly easier to obtain than snow mass indicators from remote sensing, could be used to model the influence of the snowpack on peak NDVI at regional scale.