Published in
Royal Society of Chemistry, RSC Chemical Biology, 10(4), p. 760-764, 2023
DOI: 10.1039/d3cb00131h
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Binding affinity-based intracellular drug detection enabled by a unimolecular cucurbit[7]uril-dye conjugate
Journal article published in 2023 by
Yanxi Liu,
Changming Hu,
Julian A. Serna,
Frank Biedermann 
,
Pavel A. Levkin
,
Pavel A. Levkin
This paper is made freely available by the publisher.
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Abstract
We demonstrate an application of macrocyclic cucurbit[7]uril (CB7) host covalently coupled to a nitrobenzoxadiazole (NBD) fluorescent dye (CB7-NBD conjugate) as a sensor for detecting diverse analytes in the intracellular compartment of live cells.