Published in
American Society of Clinical Oncology, JCO Precision Oncology, 7, 2023
DOI: 10.1200/po.23.00451
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Efficacy and Tolerability of Osimertinib and Sotorasib Combination Treatment for Osimertinib Resistance Caused by KRAS G12C Mutation: A Report of Two Cases
Journal article published in 2023 by
Sophie M. Ernst 
,
Sevim Uzun,
Marthe S. Paats,
Ronald van Marion ,
Peggy N. Atmodimedjo,
Evert de Jonge ,
Ron H. N. van Schaik ,
Joachim G. J. V. Aerts ,
Jan H. von der Thüsen,
Hendrikus J. Dubbink ,
Anne-Marie C. Dingemans
,
Sevim Uzun,
Marthe S. Paats,
Ronald van Marion ,
Peggy N. Atmodimedjo,
Evert de Jonge ,
Ron H. N. van Schaik ,
Joachim G. J. V. Aerts ,
Jan H. von der Thüsen,
Hendrikus J. Dubbink ,
Anne-Marie C. Dingemans
This paper is made freely available by the publisher.
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Abstract
Two cases show osimertinib/sotorasib combination could be effective in KRAS G12C-driven osimertinib resistance.