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American Physiological Society, American Journal of Physiology - Lung Cellular and Molecular Physiology, 5(326), p. L551-L561, 2024

DOI: 10.1152/ajplung.00353.2023

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Anti-inflammatory roles of type I interferon signaling in the lung

Journal article published in 2024 by Jingjing Feng, Yi Liu, Jooyoung Kim, Farida Ahangari, Naftali Kaminski ORCID, William G. Bain ORCID, Zhijun Jie, Charles S. Dela Cruz, Lokesh Sharma ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Type I interferons are known for their antiviral activities. In this study, we demonstrate a conserved anti-inflammatory role of type I interferon signaling against diverse stimuli in the lung. We show that exacerbated inflammatory response in the absence of type I interferon signaling has both acute and chronic consequences in the lung including structural changes.