AbstractThe newly emerging field of circularly polarized room-temperature phosphorescence (CP-RTP) has experienced rapid growth due to the intriguing photophysical properties and wide-ranging potential applications of such materials. Of particular interest are the purely organic CP-RTPs, as they offer excellent biocompatibility, versatile tunability, and cost-effectiveness. These materials show promising applications in fields including biological imaging, photodiodes, intelligent sensing, information storage, and three-dimensional displays. To deepen our understanding of the luminescence mechanism and broaden the envisioned scope, herein, we summarize them based on chirality character, including point, axial, planar, and other chiral systems. This review aims to scrutinize missing clues and envision future development in the area.1 Introduction2 Photophysics of CP-RTP3 Purely Organic CP-RTP Materials3.1 CP-RTP Systems based on Point Chirality3.2 CP-RTP Systems based on Axial Chirality3.3 CP-RTP Systems based on Planar Chirality and Others4 Conclusion