Wiley, Clinical and Experimental Dermatology, 2024
DOI: 10.1093/ced/llae136
Full text: Unavailable
A 32-year-old woman presented with a 3-year history of progressive skin thickening. On examination, the skin of the glabella was thickened with longitudinal furrows, resulting in leonine facies. Skin-coloured to reddish-brown, firm, waxy, closely spaced papules partially coalescing to form sheets of induration with circular punched-out areas of sparing in between over the face, neck, trunk, abdomen, arms and thighs were seen. She additionally complained of a tingling sensation and occasional pain over the lateral side of her hands. Punch biopsy obtained from a papule over the nape of the neck revealed fibroblast proliferation with collagen and mucin deposition in the upper and midreticular dermis.