Published in
Royal Society of Chemistry, RSC Chemical Biology, 8(4), p. 587-591, 2023
DOI: 10.1039/d3cb00050h
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Siderocalin fusion proteins enable a new <sup>86</sup>Y/<sup>90</sup>Y theranostic approach
Journal article published in 2023 by
Alexia G. Cosby 
,
Trevor Arino,
Tyler A. Bailey ,
Matthew Buerger,
Joshua J. Woods ,
Luis M. Aguirre Quintana ,
Jennifer V. Alvarenga Vasquez,
Jennifer N. Wacker ,
Alyssa N. Gaiser ,
Roland K. Strong,
Rebecca J. Abergel
,
Trevor Arino,
Tyler A. Bailey ,
Matthew Buerger,
Joshua J. Woods ,
Luis M. Aguirre Quintana ,
Jennifer V. Alvarenga Vasquez,
Jennifer N. Wacker ,
Alyssa N. Gaiser ,
Roland K. Strong,
Rebecca J. Abergel
This paper is made freely available by the publisher.
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Abstract
The mammalian protein siderocalin binds hydroxypyridinone complexes of trivalent rare-earth metals and f-elements through cation-π and electrostatic interactions. It can also be fused with biological vectors for the targeted delivery of imaging and therapeutic radionuclides.