Published in
Royal Society of Chemistry, Chemical Science, 22(14), p. 5918-5924, 2023
DOI: 10.1039/d3sc01880f
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Organocatalytic intramolecular (4 + 2) annulation of enals with ynamides: atroposelective synthesis of axially chiral 7-aryl indolines
Journal article published in 2023 by
Zhi-Xin Zhang,
Li-Gao Liu,
Yi-Xi Liu,
Jian Lin,
Xin Lu 
,
Long-Wu Ye ,
Bo Zhou
,
Long-Wu Ye ,
Bo Zhou
This paper is made freely available by the publisher.
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Abstract
An organocatalytic intramolecular (4 + 2) annulation of enals with ynamides is disclosed, providing a convenient way to axially chiral indolines. The synthesized axially chiral skeleton was proved to be potentially applicable as a chiral ligand.