AbstractThe Southern Ocean is a major region of ocean carbon uptake, but its future changes remain uncertain under climate change. Here we show the projected shift in the Southern Ocean CO₂ sink using a suite of Earth System Models, revealing changes in the mechanism, position and seasonality of the carbon uptake. The region of dominant CO₂ uptake shifts from the Subtropical to the Antarctic region under the high-emission scenario. The warming-driven sea-ice melt, increased ocean stratification, mixed layer shoaling, and a weaker vertical carbon gradient is projected to together reduce the winter de-gassing in the future, which will trigger the switch from mixing-driven outgassing to solubility-driven uptake in the Antarctic region during the winter season. The future Southern Ocean carbon sink will be poleward-shifted, operating in a hybrid mode between biologically-driven summertime and solubility-driven wintertime uptake with further amplification of biologically-driven uptake due to the increasing Revelle Factor.