The global rise in the elderly population accentuates the importance of addressing challenges associated with aging, including comorbidities and declining physical function. Variability in the aging process emphasizes the potential for evidence-based biomedical innovations. Robust trials for anti-aging interventions become vital as public interest grows. Despite promising biomedical innovations, practical implementation encounters social and ethical challenges. Ensuring credibility in anti-aging research requires collaboration with biogerontology-focused journals and peer reviewers. This opinion piece delves into the unique aspects and challenges of anti-aging research and the pivotal role of adherence to reporting standards in advancing healthy aging initiatives.