Background: Microtia is a congenital anomaly of the ear. We present an innovative technique using a 3D personalized framework that could simplify and standardize the sculpting phase, thanks to reverse engineering and additive manufacturing techniques. Methods: Three-dimensional models were realized by T3Ddy, a joint laboratory between the department of industrial engineering and Meyer Children’s Hospital. Data were obtained retrospectively and included patient demographics, primary diagnosis, side of the affected ear, microtia classification, surgical time, length of hospitalization, type of skin approach and framework, complications, aesthetic results, and level of satisfaction using specific questionnaires. Data are reported as median and IQR. Results: A total of 17 children (female gender: four) underwent auricular reconstruction surgery with autologous cartilage in our center, between 2019 and 2022. Median age at surgery was 14 years [interquartile range (IQR), 13–17], and the median hospitalization length was 5 days (IQR, 3–5). Median surgical time was 420 minutes (IQR, 406–452). Complications occurred in four patients out of 19 procedures, with a complication rate of 21%. Aesthetic results were satisfactory in all cases. Conclusions: The three-dimensional models allow for an intuitive and precise approach. Having developed specific models for each component of the framework, we aimed to improve the aesthetic result and simplify the surgical intervention, guaranteeing a standardized yet personalized experience for each patient. The interprofessional partnership is fundamental to achieving this result.