Preview Periodontitis is a chronic disease associated with a dysbiotic oral microbiota that, in predisposed hosts, causes the perseverance, for years and years, of a local inflammation of periodontal tissues, promoting the progressive destruction of the supporting structures of the teeth1. Recent evidence supports the potential deleterious impacts of periodontitis, not only topically, but also on systemic health and mortality2,3. Periodontitis has been related with increased risk of developing or manifesting diseases, such as diabetes, obesity, cardiovascular disorders, hypertension, cancer, chronic renal disease, pneumonia, rheumatoid arthritis, adverse pregnancy outcomes, and obstructive lung diseases4-7. Moreover, the presence of oral pathogens in the circulation has been associated with atheroma formation and dyslipidaemia4. [ … ]