AbstractHigh‐grade metamorphic rocks are widely exposed along the SE–NW‐ to E–W‐trending shear zones in the Truong Son Belt, Central Vietnam, but few petrological studies have been conducted in this area. Herein, we report the occurrence of mylonitized granulites that crop out along the Dai Loc shear zone in the southernmost Truong Son Belt. Detailed petrographic analysis, geochemistry and P–T–t estimates of the evolution of two granulite samples are presented to elucidate the formation processes of these high‐grade metamorphic rocks. The results indicate that the rocks underwent two distinct metamorphic cycles. The first cycle (M1) is characterized by coarse‐grained granulite mineral assemblages, defining a tight clockwise P–T path with near‐isobaric heating to a near ultrahigh‐temperature peak at low pressure, followed by cooling. The prograde mineral assemblage (M1a) is indicated by inclusions of cordierite + sillimanite + biotite + quartz + spinel ± plagioclase in coarse‐grained garnet, orthopyroxene and cordierite. The mineral assemblage of garnet + orthopyroxene + cordierite + plagioclase + K‐feldspar + ilmenite + melt ± biotite (M1b) defines the peak P–T conditions of 5.3–6.3 kbar and 850–920°C. Post‐peak cooling (M1c) is marked by the formation of quartz + biotite symplectites around garnet and orthopyroxene. The second cycle involved medium‐pressure amphibolite facies metamorphism (M2), characterized by domainal development of fine‐grained kyanite‐bearing mineral associations. Petrographic observations indicate that these fine‐grained associations were formed during mylonitization. Zircon U–Pb dating reveals that the timing of granulite facies metamorphism appears to be coeval with the intrusion of a post‐collisional granitoid at 430–410 Ma. Granulite facies metamorphism and crustal melting were probably driven by asthenospheric mantle upwelling triggered by slab breakoff during the Early Palaeozoic. Considering previous structural and geochronological studies, the second metamorphic event likely occurred during the Triassic Indosinian orogeny.