Traditional hand rehabilitation devices present a challenge in providing personalized training that can lead to finger movements exceeding the safe range, resulting in secondary injuries. To address this issue, we introduce a soft rehabilitation training glove with the function of safety and personalization, which can allow patients to select training modes based on rehabilitation and provide real-time monitoring, as well as feedback on finger movement data. The inner glove is equipped with bending sensors to access the maximum/minimum angle of finger movement and to provide data for the safety of rehabilitation training. The outer glove contains flexible drivers, which can drive fingers for different modes of rehabilitation training. As a result, the rehabilitation glove can drive five fingers to achieve maximum extension/flexion angles of 15.65°/85.97°, 15.34°/89.53°, 16.78°/94.27°, 15.59°/88.82°, and 16.73°/88.65°, from thumb to little finger, respectively, and the rehabilitation training frequency can reach six times per minute. The safety evaluation result indicated an error within ±6.5° of the target-motion threshold. The reliability assessment yielded a high-intra-class correlation coefficient value (0.7763–0.9996). Hence, the rehabilitation glove can achieve targeted improvement in hand function while ensuring safety.