Published in

Nature Research, Nature Cell Biology, 8(6), p. 696-697, 2004

DOI: 10.1038/ncb0804-696

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Loss of Dicer fowls up centromeres

Journal article published in 2004 by Sharon A. White, Robin C. Allshire ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Centromeres, specialized regions on chromosomes, are essential for accurate chromosome segregation during cell division. In fission yeast, the RNA interference machinery has a pivotal function in the assembly of centromeric heterochromatin, which mediates sister centromere cohesion. Studies in vertebrate cells now suggest that many aspects of this process are conserved.