Effect of low-dose tamoxifen after surgical excision of ductal intraepithelial neoplasia: results of a large retrospective monoinstitutional cohort study
Journal article published in 2013 by
A. Guerrieri-Gonzaga,
M. Lazzeroni,
E. Botteri,
D. Serrano 
,
N. Rotmensz,
Mc-C. Varricchio,
M. Cazzaniga,
G. Bollani,
S. Mora,
C. Montefrancesco,
G. Pruneri,
G. Viale,
M. Intra,
V. Galimberti,
A. Goldhirsch
and other authors.
,
N. Rotmensz,
Mc-C. Varricchio,
M. Cazzaniga,
G. Bollani,
S. Mora,
C. Montefrancesco,
G. Pruneri,
G. Viale,
M. Intra,
V. Galimberti,
A. Goldhirsch
and other authors.
This paper is made freely available by the publisher.
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Abstract
Postsurgical treatment of ductal intraepithelial neoplasia (DIN) with standard doses of tamoxifen has not reached a consensus yet. Given positive results of low-dose tamoxifen on breast cancer biomarkers modulation, we analyzed a large cohort of DIN patients treated with low-dose tamoxifen or no treatment as per institutional guidelines