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American Chemical Society, Journal of Organic Chemistry, 3(79), p. 1406-1417, 2014

DOI: 10.1021/jo402658h

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Synthesis and Characterization of Glycoconjugated Porphyrin Triphenylamine Hybrids for Targeted Two-Photon Photodynamic Therapy

Journal article published in 2014 by Fabien Hammerer, Guillaume Garcia, Su Chen, Florent Poyer, Sylvain Achelle, Celine Fiorini-Debuisschert, Marie-Paule Teulade-Fichou, Philippe-H. Maillard
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

In order to avoid side effects at the time of cancer eradication to the patients, the selectivity of treatments has become of strategic importance. In the case of photodynamic therapy (PDT), two-photon absorption combined with active targeting of tumors could allow both spatial and chemical selectivity. In this context, we present the synthesis, spectroscopic, and biological properties of a series of porphyrin-triphenylamine hybrids with excellent singlet oxygen production capacities and good two-photon absorption.