Dissemin is shutting down on January 1st, 2025

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Oxford University Press, Military Medicine, 11-12(186), p. 1254-1256, 2021

DOI: 10.1093/milmed/usab132

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Accelerated Progression of Disseminated Coccidioidomycosis Following SARS-CoV-2 Infection: A Case Report

Journal article published in 2021 by Daniel S. Krauth, Christina M. Jamros, Shayna C. Rivard, Niels H. Olson ORCID, Ryan C. Maves
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT We describe a patient with subclinical coccidioidomycosis who experienced rapid disease dissemination shortly after SARS-CoV-2 infection, suggesting host immune response dysregulation to coccidioidomycosis by SARS-CoV-2. We hypothesize that disrupted cell-mediated signaling may result after SARS-CoV-2 infection leading to functional exhaustion and CD8+ T-cell senescence with impairment in host cellular response to Coccidioides infection.