Published in
American Society for Microbiology, Journal of Virology, 13(95), 2021
DOI: 10.1128/jvi.02413-20
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Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B
Journal article published in 2021 by
Noémie Lejeune,
Florian Poulain,
Kévin Willemart,
Zoé Blockx,
Sarah Mathieu,
Nicolas A. Gillet 
This paper is made freely available by the publisher.
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Abstract
The APOBEC3 family of cytosine deaminases has important roles in antiviral innate immunity and cancer. Notably, APOBEC3A and APOBEC3B are actively upregulated by several DNA tumor viruses and contribute to transformation by introducing mutations in the cellular genome.