The last decade has seen an explosion in the uptake of digital health interventions (DHI) to address complex chronic diseases. This is particularly true in the case of multiple sclerosis where those living with the disease are increasingly seeking adjuvant treatment options such as lifestyle management. This paper seeks to give perspectives and insights from public health researchers that have engaged in the digital transformation process of a face-to-face lifestyle management educational program. There is a dearth of information regarding the digital transformation of lifestyle educational programs and this is particularly true for programs directed at chronic diseases. A large body of work exists from higher education, an area that has undergone rapid digital transformation of its work, and much can be derived from this field. There is also a well-established field of design methodologies and frameworks available to researchers seeking to design, develop and implement DHIs. This paper provides a practical overview of the synthesis between digital transformation processes in higher education and the application of an existing development framework for DHIs. By describing this process, we hope to fill an existing gap within the literature that will provide a valuable tool for future researchers.