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Nature Research, Nature Methods, 6(8), p. 481-483, 2011

DOI: 10.1038/nmeth.1604

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Combining quantitative proteomics data processing workflows for greater sensitivity

Journal article published in 2011 by Niklaas Colaert, Christophe Van Huele, Sven Degroeve, An Staes, Joël Vandekerckhove, Kris Gevaert ORCID, Lennart Martens ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We here describe a normalization method to combine quantitative proteomics data. By merging the output of two popular quantification software packages, we obtained a 20% increase (on average) in the number of quantified human proteins without suffering from a loss of quality. Our integrative workflow is freely available through our user-friendly, open-source Rover software (http://compomics-rover.googlecode.com/).