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Elsevier, Journal of Bioscience and Bioengineering, 1(113), p. 26-29, 2012

DOI: 10.1016/j.jbiosc.2011.09.007

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Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid

Journal article published in 2012 by Wei Boon Yap, Beng Ti Tey ORCID, Noorjahan Banu Mohamed Alitheen, Wen Siang Tan ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The C-terminal domain of Nipah virus (NiV) nucleocapsid protein (NP₄₀₁₋₅₃₂) was inserted at the N-terminus and the immunodominant loop of hepatitis B core antigen (HBc). The stability of NP₄₀₁₋₅₃₂ increased tremendously when displayed on the HBc particles. These particles reacted specifically with the swine anti-NiV and the human anti-HBc antisera.