Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

Zekavat, Seyedeh M.; Consortium, FinnGen; Lin, Shu-Hong; Liu, Xiaoxi; Bick, Alexander G.; Liu, Aoxing; Paruchuri, Kaavya; Koyama, Satoshi; Ito, Kaoru; Momozawa, Yukihide; Matsuda, Koichi; Wang, Chen; Yamanashi, Yuji; Furukawa, Yoichi; Morisaki, Takayuki; Murakami, Yoshinori; Muto, Kaori; Uddin, Md Mesbah; Ziemann, Adam; Nagai, Akiko; Obara, Wataru; Yamaji, Ken; Takahashi, Kazuhisa; Ye, Yixuan; Asai, Satoshi; Takahashi, Yasuo; Suzuki, Takao; Sinozaki, Nobuaki; Yamaguchi, Hiroki; Yu, Zhaolong; Minami, Shiro; Murayama, Shigeo; Yoshimori, Kozo; Nagayama, Satoshi; Obata, Daisuke; Higashiyama, Masahiko; Masumoto, Akihide; Kamatani, Yoichiro; Koretsune, Yukihiro; Palotie, Aarno; Mitchell, Adele; Huertas-Vazquez, Adriana; Bhattacharya, Romit; Salminen, Aino; Jussila, Airi; Havulinna, Aki; Mackay, Alex; Abbasi, Ali; Pirruccello, James P.; Elliott, Amanda; Cole, Amy; Shcherban, Anastasia; Mälarstig, Anders; Pampana, Akhil; Loboda, Andrey; Podgornaia, Anna; Lehtonen, Anne; Pitkäranta, Anne; Loh, Po-Ru; Remes, Anne; Auranen, Annika; Hakanen, Antti; Palomäki, Antti; Kohli, Puja; Jalanko, Anu; Loukola, Anu; Chhibber, Aparna; Lertratanakul, Apinya; Lehisto, Arto; McCarroll, Steven A.; Mannermaa, Arto; Hedman, Åsa; Chu, Audrey; Madar, Aviv; Kiryluk, Krzysztof; van Adelsberg, Janet; Ghazal, Awaisa; Challis, Benjamin; Sun, Benjamin; Cummings, Beryl; Riley-Gillis, Bridget; Neale, Benjamin; Fox, Caroline; Chen, Chia-Yen; Wang, Clarence; Chatelain, Clement; Zierer, Jonas; Ionita-Laza, Iuliana; Gordin, Daniel; Quarless, Danjuma; Oh, Danny; Choy, David; Close, David; Engels, Eric A.; Pulford, David; Rice, David; Waterworth, Dawn; Rajpal, Deepak; Brown, Derek W.; Baird, Denis; Jambulingam, Dhanaprakash; Chang, Diana; Kulkarni, Diptee; Paul, Dirk; Liu, Dongyu; Smoller, Jordan W.; Teng, Edmond; de Lange, Katrina; Punkka, Eero; Ekholm, Eeva; Kangasniemi, Eeva; Laakkonen, Eija; Green, Robert; Wigmore, Eleonor; Järvensivu, Elina; Kilpeläinen, Elina; Widen, Elisabeth; Tsai, Ellen; Karlson, Elizabeth W.; Mohammed, Elmutaz; Strauss, Erich; Kvikstad, Erika; Pitkänen, Esa; Lebo, Matthew; Kaiharju, Essi; Xu, Ethan; Xu, Fanli; Rahimov, Fedik; Vaura, Felix; Ellinor, Patrick T.; Auge, Franck; Brein, Georg; Lassi, Glenda; Heap, Graham; Laivuori, Hannele; Weiss, Scott T.; Mattsson, Hannele; Uusitalo-Järvinen, Hannele; Kankaanranta, Hannu; Uusitalo, Hannu; Chen, Hao; Daly, Mark J.; Siirtola, Harri; Joensuu, Heikki; Runz, Heiko; Lehtonen, Heli; Heyne, Henrike; Soininen, Hilkka; Jacob, Howard; Chen, Hubert; Shen, Huei-Yi; Xu, Huilei; Vähätalo, Iida; Kalliala, Ilkka; Tachmazidou, Ioanna; Kaprio, Jaakko; Parkkinen, Jaakko; Jacob, Jaison; Kumar, Janet; Laukkanen, Jari; Ritari, Jarmo; Garcia-Tabuenca, Javier; Waring, Jeffrey; Schutzman, Jennifer; Liu, Jimmy; Lee, Jiwoo; Betts, Joanna; Rämö, Joel; Huhtakangas, Johanna; Mäkelä, Johanna; Mattson, Johanna; Schleutker, Johanna; Kettunen, Johannes; Eicher, John; Chung, Jonathan; Turunen, Joni A.; Gordillo, Jorge Esparza; Maranville, Joseph; Karjalainen, Juha; Mehtonen, Juha; Rinne, Juha; Sinisalo, Juha; Junttila, Juhani; Ganna, Andrea; Koskela, Jukka; Partanen, Jukka; Peltola, Jukka; Hunkapiller, Julie; Pihlajamäki, Jussi; Wade, Justin; Partanen, Juulia; Mäkikallio, Kaarin; Kaarniranta, Kai; Tasanen, Kaisa; Metsärinne, Kaj; Pärn, Kalle; King, Karen S.; Eklund, Kari; Linden, Kari; Zhou, Wei; Nieminen, Kari; Hannula-Jouppi, Katariina; Call, Katherine; Klinger, Katherine; Donner, Kati; Hyvärinen, Kati; Kristiansson, Kati; Kaukinen, Katri; Pylkäs, Katri; Usiskin, Keith; Palin, Kimmo; Shkura, Kirill; Auro, Kirsi; Kalpala, Kirsi; Sipilä, Kirsi; Elenius, Klaus; Tsuo, Kristin; Lahtela, L. Elisa; Elisa Lahtela, L.; Addis, Laura; Huilaja, Laura; Kotaniemi-Talonen, Laura; Mustaniemi, Laura; Pirilä, Laura; Morin-Papunen, Laure; Aaltonen, Lauri; Koulu, Leena; Suominen, Liisa; Kallio, Lila; McCarthy, Linda; Männikkö, Lotta; Obeidat, Maen; Rivas, Manuel; Hautalahti, Marco; Pelkonen, Margit; Kaunisto, Mari; Niemi, Mari E.; Siponen, Maria; Crohns, Marika; Kalaoja, Marita; Luodonpää, Marja; Vääräsmäki, Marja; Taskinen, Marja-Riitta; Tuppurainen, Marjo; McCarthy, Mark; Laakso, Markku; Laukkanen, Markku; Voutilainen, Markku; Juonala, Markus; Perola, Markus; Hochfeld, Marla; Färkkilä, Martti; Reeve, Mary Pat; Kanai, Masahiro; Brauer, Matt; Kivinen, Katja; Gossel, Matthias; Peura, Matti; Ehm, Meg; Miller, Melissa; Liu, Mengzhen; Aavikko, Mervi; Koskinen, Miika; Helminen, Mika; Kähönen, Mika; Arvas, Mikko; Hiltunen, Mikko; Kiviniemi, Mikko; Caliskan, Minal; Karjalainen, Minna; Raivio, Minna; Koivusalo, Mirkka; Kurki, Mitja; Maasha, Mutaamba; Bing, Nan; Bowers, Natalie; Raghavan, Neha; Renaud, Nicole; Välimäki, Niko; Hautala, Nina; Mars, Nina; Pitkänen, Nina; Smaoui, Nizar; Kaipiainen-Seppänen, Oili; Carpén, Olli; Dada, Oluwaseun A.; Soylemez, Onuralp; Heikinheimo, Oskari; Tuovila, Outi; Uimari, Outi; Gormley, Padhraig; Auvinen, Päivi; Laiho, Päivi; Mäntylä, Päivi; Polo, Päivi; Bronson, Paola; Kauppi, Paula; Karihtala, Peeter; Nieminen, Pekka; Tienari, Pentti; Virolainen, Petri; Isomäki, Pia; Parolo, Pietro Della Briotta; Della Briotta Parolo, Pietro; Pussinen, Pirkko; Palta, Priit; Pakkanen, Raimo; Serpi, Raisa; Mishra, Rajashree; Hinttala, Reetta; Kälviäinen, Reetta; Wong, Regis; Popovic, Relja; Siegel, Richard; Lahesmaa, Riitta; Kajanne, Risto; Graham, Robert; Plenge, Robert; Yang, Robert; Kallionpää, Roosa; Tian, Ruoyu; Miller, Russell; Esmaeeli, Sahar; Kauppila, Saila; John, Sally; Heikkinen, Sami; Koskelainen, Sami; Wadhawan, Samir; Pikkarainen, Sampsa; Heron, Samuel; Ripatti, Samuli; Seitsonen, Sanna; Lahdenperä, Sanni; Ruotsalainen, Sanni; Pendergrass, Sarah; Smith, Sarah; Vuoti, Sauli; Hassan, Shabbeer; Biswas, Shameek; Luo, Shuang; Rüeger, Sina; Lähteenmäki, Sini; Peltonen, Sirkku; Soini, Sirpa; Petrovski, Slavé; Ghosh, Soumitra; McDonough, Stefan; Loomis, Stephanie; Greenberg, Steven; Eaton, Susan; Lemmelä, Susanna; Xia, Tai-He; Laitinen, Tarja; Tukiainen, Taru; Salmi, Teea; Niiranen, Teemu; Paajanen, Teemu; Kuopio, Teijo; Kilpi, Terhi; Ollila, Terhi; Hiekkalinna, Tero; Jyrhämä, Tero; Harju, Terttu; Luukkaala, Tiina; Tuomi, Tiinamaija; Behrens, Tim; Lu, Tim; Blomster, Timo; Terao, Chikashi; Sipilä, Timo P.; Southerington, Tom; Mäkelä, Tomi; Kiiskinen, Tuomo; Mantere, Tuomo; Zhao, Hongyu; Meretoja, Tuomo; Bhangale, Tushar; Salo, Tuula; Sistonen, Tuuli; Palotie, Ulla; Ebert, Benjamin L.; Gursoy, Ulvi; Kujala, Urho; Julkunen, Valtteri; Salomaa, Veikko; Reilly, Muredach P.; Kosma, Veli-Matti; Rathinakannan, Venkat Subramaniam; Kurra, Venla; Aaltonen, Vesa; Neduva, Victor; Llorens, Vincent; Sinha, Vishal; Anttonen, Vuokko; Machiela, Mitchell J.; Fleuren, Wilco; Chen, Xing; Hu, Xinli; Wu, Ying; Huang, Yunfeng; Genovese, Giulio; Natarajan, Pradeep; And,

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Nature Research, Nature Medicine, 6(27), p. 1012-1024, 2021

DOI: 10.1038/s41591-021-01371-0

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Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

Journal article published in 2021 by Seyedeh M. Zekavat, FinnGen Consortium, Shu-Hong Lin, Xiaoxi Liu, Alexander G. Bick, Aoxing Liu

, Kaavya Paruchuri, Satoshi Koyama, Kaoru Ito, Yukihide Momozawa, Koichi Matsuda, Chen Wang, Yuji Yamanashi, Yoichi Furukawa, Takayuki Morisaki and other authors.

This paper is made freely available by the publisher.

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Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection