Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 9(65), 2021
DOI: 10.1128/aac.00244-21
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Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus
Journal article published in 2021 by
Nicole N. Haese,
Nicholas A. May,
Sharon Taft-Benz,
Omar Moukha-Chafiq,
Nikhil Madadi,
Sixue Zhang 
,
Shuklendu D. Karyakarte,
Kevin J. Rodzinak,
Theresa H. Nguyen,
Michael Denton,
Aaron D. Streblow,
Nichole A. Towers,
Lynn Rasmussen,
Robert J. Bostwick,
Joseph A. Maddry
and other authors.
,
Shuklendu D. Karyakarte,
Kevin J. Rodzinak,
Theresa H. Nguyen,
Michael Denton,
Aaron D. Streblow,
Nichole A. Towers,
Lynn Rasmussen,
Robert J. Bostwick,
Joseph A. Maddry
and other authors.
This paper is made freely available by the publisher.
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Abstract
Venezuelan equine encephalitis virus (VEEV) is a reemerging alphavirus that can cause encephalitis resulting in severe human morbidity and mortality. Using a high-throughput cell-based screen, we identified a quinolinone compound that protected against VEEV-induced cytopathic effects.