Heparanized chitosans: towards the third generation of chitinous biomaterials
Journal article published in 2021 by
Julia Revuelta 
,
Isabel Fraile ,
Dianelis T. Monterrey ,
Nerea Peña,
Raúl Benito-Arenas ,
Agatha Bastida ,
Alfonso Fernández-Mayoralas ,
Eduardo García-Junceda
,
Isabel Fraile ,
Dianelis T. Monterrey ,
Nerea Peña,
Raúl Benito-Arenas ,
Agatha Bastida ,
Alfonso Fernández-Mayoralas ,
Eduardo García-Junceda
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Abstract
Sulfation of chitosan makes this polymer a closer mimic of heparins and heparan sulfates, giving rise to the so called heparanized chitosan, that exert their biological activities through their capacity to interact with a range of biological targets.