Toxoplasma gondii Toxolysin 4 Contributes to Efficient Parasite Egress from Host Cells
Journal article published in 2021 by
My-Hang Huynh,
Marijo S. Roiko 
,
Angelica O. Gomes,
Ellyn N. Schinke,
Aric J. Schultz,
Swati Agrawal,
Christine A. Oellig,
Travis R. Sexton,
Jessica M. Beauchamp,
Julie Laliberté,
Komagal Kannan Sivaraman,
Louis B. Hersh,
Sheena McGowan,
Vern B. Carruthers
,
Angelica O. Gomes,
Ellyn N. Schinke,
Aric J. Schultz,
Swati Agrawal,
Christine A. Oellig,
Travis R. Sexton,
Jessica M. Beauchamp,
Julie Laliberté,
Komagal Kannan Sivaraman,
Louis B. Hersh,
Sheena McGowan,
Vern B. Carruthers
This paper is made freely available by the publisher.
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Abstract
After replicating within infected host cells, the single-celled parasite Toxoplasma gondii must rupture out of such cells in a process termed egress. Although it is known that T. gondii egress is an active event that involves disruption of host-derived membranes surrounding the parasite, very few proteins that are released by the parasite are known to facilitate egress.