Published in
American Society for Microbiology, Journal of Virology, 18(95), 2021
DOI: 10.1128/jvi.00796-21
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Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells
Journal article published in 2021 by
Sai Priya Anand,
Shilei Ding,
William D. Tolbert,
Jérémie Prévost,
Jonathan Richard,
Hwi Min Gil,
Gabrielle Gendron-Lepage,
Wing-Fai Cheung,
Haifeng Wang,
Rebecca Pastora,
Hirak Saxena,
Warren Wakarchuk 
,
Halima Medjahed,
Bruce D. Wines,
Mark Hogarth
and other authors.
,
Halima Medjahed,
Bruce D. Wines,
Mark Hogarth
and other authors.
This paper is made freely available by the publisher.
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Abstract
PGT121 is a highly potent bNAb and its antiviral activities for HIV-1 prevention and therapy are currently being evaluated in clinical trials. The importance of its Fc-effector functions in clearing HIV-1-infected cells is also under investigation.