Published in
American Society for Microbiology, Journal of Virology, 19(95), 2021
DOI: 10.1128/jvi.00299-21
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Targeted Long-Read Sequencing Reveals Comprehensive Architecture, Burden, and Transcriptional Signatures from Hepatitis B Virus-Associated Integrations and Translocations in Hepatocellular Carcinoma Cell Lines
Journal article published in 2021 by
Ricardo Ramirez,
Nicholas van Buuren 
,
Lindsay Gamelin,
Cameron Soulette,
Lindsey May,
Dong Han,
Mei Yu,
Regina Choy,
Guofeng Cheng,
Neeru Bhardwaj,
Joy Chiu,
Robert C. Muench,
William E. Delaney,
Hongmei Mo,
Becket Feierbach
and other authors.
,
Lindsay Gamelin,
Cameron Soulette,
Lindsey May,
Dong Han,
Mei Yu,
Regina Choy,
Guofeng Cheng,
Neeru Bhardwaj,
Joy Chiu,
Robert C. Muench,
William E. Delaney,
Hongmei Mo,
Becket Feierbach
and other authors.
This paper is made freely available by the publisher.
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Abstract
HCC-derived cell lines have served as practical models to study HBV biology for decades. These cell lines harbor multiple HBV integrations and express only HBV surface antigen (HBsAg).