Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer
Journal article published in 2021 by
William D. Tolbert,
Dung N. Nguyen,
Zahra Rikhtegaran Tehrani,
Mohammad M. Sajadi,
Marzena Pazgier 
This paper is made freely available by the publisher.
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Abstract
Binding to target cell CD4 is the first crucial step required for HIV-1 infection. Thus, the CD4-binding site (CD4bs) is one of the most accessible sites for antibodies (Abs).