American Society for Microbiology, mSystems, 4(6), 2021
DOI: 10.1128/msystems.00392-21
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Sequencing the genomes of the circulating SARS-CoV-2 strains is the only way to monitor the viral spread and evolution of the virus. Two different approaches, namely, tiling multiplex PCR and sequence hybridization by bait capture, are commonly used to fulfill this task.