Published in
American Society for Microbiology, mSystems, 4(6), 2021
DOI: 10.1128/msystems.00306-21
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Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics
Journal article published in 2021 by
Orna Ernst,
Mohd M. Khan,
Benjamin L. Oyler,
Sung Hwan Yoon 
,
Jing Sun,
Fang-Yu Lin,
Nathan P. Manes ,
Alexander D. MacKerell,
Iain D. C. Fraser,
Robert K. Ernst ,
David R. Goodlett,
Aleksandra Nita-Lazar
,
Jing Sun,
Fang-Yu Lin,
Nathan P. Manes ,
Alexander D. MacKerell,
Iain D. C. Fraser,
Robert K. Ernst ,
David R. Goodlett,
Aleksandra Nita-Lazar
This paper is made freely available by the publisher.
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Abstract
Macrophages and monocytes are innate immune cells playing an important role in orchestrating the initial innate immune response to bacterial infection and the tissue damage. This response is facilitated by specific receptors on the cell surface and intracellularly.