It is well known that wildfires destroy vegetation and form soil crusts, both of which increase stormwater runoff that accelerates erosion, but less attention has been given to wildfire impacts on groundwater aquifers. Here, we present a systematic study across the contiguous United States to test the hypothesis that wildfires reduce infiltration, indicated by temporary reductions in groundwater levels. Geographic information systems (GIS) analysis performed using structured queried language (SQL) categorized wildfires by their proximity to wells with publicly available monitoring data. Although numerous wildfires were identified with nearby monitoring wells, most of these data were confounded by unknown processes, preventing a clear acceptance or rejection of the hypothesis. However, this analysis did identify a particular case study, the 1996 Honey Boy Fire in Beaver County, Utah, USA that supports the hypothesis. At this site, daily groundwater data from a well located 790 m from the centroid of the wildfire were used to assess the groundwater level before and after the wildfire. A sinusoidal time series adjusted for annual precipitation matches groundwater level fluctuations before the wildfire but cannot explain the approximately two-year groundwater level reduction after the wildfire. Thus, for this case study, there is a correlation, which may be causal, between the wildfire and temporary reduction in groundwater levels. Generalizing this result will require further research.