Published in
American Society for Microbiology, Journal of Virology, 22(95), 2021
DOI: 10.1128/jvi.00387-21
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Human AdV-20-42-42, a Promising Novel Adenoviral Vector for Gene Therapy and Vaccine Product Development
Journal article published in 2021 by
Mónika Z. Ballmann,
Svjetlana Raus,
Ruben Engelhart,
Győző L. Kaján,
Abdelaziz Beqqali,
Patrick W. F. Hadoke,
Chantal van der Zalm,
Tibor Papp,
Lijo John 
,
Selina Khan,
Satish Boedhoe,
Katarina Danskog,
Jerome Custers,
Lars Frängsmyr,
Wilfried A. M. Bakker
and other authors.
,
Selina Khan,
Satish Boedhoe,
Katarina Danskog,
Jerome Custers,
Lars Frängsmyr,
Wilfried A. M. Bakker
and other authors.
This paper is made freely available by the publisher.
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Abstract
Adenoviral vectors are under investigation for a broad range of therapeutic indications in diverse fields, such as oncology and gene therapy, as well as for vaccination both for human and veterinary use. A wealth of data shows that preexisting immune responses may limit the use of a vector.