The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection
Journal article published in 2021 by
Nicole A. Loeven,
Andrew I. Perault,
Peggy A. Cotter,
Craig A. Hodges,
Joseph D. Schwartzman,
Thomas H. Hampton 
,
James B. Bliska
,
James B. Bliska
This paper is made freely available by the publisher.
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Abstract
B. cenocepacia is often considered the most virulent species in the Bcc because of its close association with cepacia syndrome in addition to its capacity to cause chronic lung infections in CF patients (1). Prior to the current study, virulence factors of B. cenocepacia important for causing lethal disease had not been identified in a CF animal model of lung infection.