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American Physiological Society, American Journal of Physiology - Renal Physiology, 5(321), p. F645-F655, 2021

DOI: 10.1152/ajprenal.00207.2021

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Expression of claudin-8 is induced by aldosterone in renal collecting duct principal cells

Journal article published in 2021 by Ali Sassi ORCID, Yubao Wang, Alexandra Chassot, Isabelle Roth, Suresh Ramakrishnan, Valérie Olivier ORCID, Olivier Staub ORCID, Khalil Udwan, Eric Feraille ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

In this study, we showed that aldosterone modulates claudin-8 expression in cultured collecting duct principal cells and in the mouse kidney. The upregulation of claudin-8 expression in response to aldosterone is dependent on at least glycogen synthase kinase-3, Lyn, and Abl signaling pathways, indicating the participation of multiple protein kinases to the effect of aldosterone.