Published in
American Association for the Advancement of Science, Science Advances, 44(7), 2021
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Ryanodine receptor leak triggers fiber Ca <sup>2+</sup> redistribution to preserve force and elevate basal metabolism in skeletal muscle
Journal article published in 2021 by
Cedric R. Lamboley 
,
Luke Pearce,
Crystal Seng ,
Aldo Meizoso-Huesca ,
Daniel P. Singh ,
Barnaby P. Frankish ,
Vikas Kaura ,
Harriet P. Lo,
Charles Ferguson,
Paul D. Allen,
Philip M. Hopkins ,
Robert G. Parton ,
Robyn M. Murphy ,
Chris van der Poel ,
Christopher J. Barclay
and other authors.
,
Luke Pearce,
Crystal Seng ,
Aldo Meizoso-Huesca ,
Daniel P. Singh ,
Barnaby P. Frankish ,
Vikas Kaura ,
Harriet P. Lo,
Charles Ferguson,
Paul D. Allen,
Philip M. Hopkins ,
Robert G. Parton ,
Robyn M. Murphy ,
Chris van der Poel ,
Christopher J. Barclay
and other authors.
This paper is made freely available by the publisher.
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Abstract
RyR1 Ca 2+ leak causes a cascade of events that shifts Ca 2+ to the cytoplasm and mitochondria, supporting force generation.