Cuscuta mantiqueirana Costea, S.S. Silva & Sim.-Bianch. a new species from montane cloud forests of the Serra da Mantiqueira, Brazil, is described and illustrated. The morphological and phylogenetic analyses revealed that the new species belongs to sect. Subulatae of subg. Grammica. The new species is related to C. odorata var. botryoides, C. rotundiflora and C. globiflora from which it differs in narrower calyx lobes and the presence of four stomatiferous lobes or projections at the distal part of the ovary. A detailed morphological comparison with C. odorata var. botryoides, morphologically the most similar taxon, is provided along with the geographical distribution, ecology and host range of the species. The morphological and phylogenetic relationships of the new species, as well as the diversity of stomatiferous projections, are discussed in the broader context of sect. Subulatae and subg. Grammica. Cuscuta boliviana var. paranensis is considered a synonym of C. odorata var. botryoides.