Optical health monitoring and treatment have been spotlighted due to their biocompatible properties. Several researchers are investigating optical devices for obtaining health signals and curing diseases without any damage to the body. In particular, μLEDs have received a lot of attention as a future light source due to their superior optical/electrical properties, environmental stability, and structural advantages. According to their strengths, μLEDs have been used for various biomedical applications, such as optogenetics and hair regrowth. In this paper, we introduce the research tendency of μLEDs and the latest bio-applications.