Published in
American Society for Microbiology, Microbiology Spectrum, 3(9), 2021
DOI: 10.1128/spectrum.00855-21
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Prolonged SARS-CoV-2 Positivity in Immunocompetent Patients: Virus Isolation, Genomic Integrity, and Transmission Risk
Journal article published in 2021 by
Isabela de Carvalho Leitão,
Pedro Telles Calil,
Rafael Mello Galliez,
Filipe Romero Rebello Moreira,
Diana Mariani,
Anna Carla Pinto Castiñeiras,
Gustavo Peixoto Duarte da Silva,
Richard Araújo Maia,
Isadora Alonso Corrêa,
Fábio Luís Lima Monteiro,
Marcos Romário Matos de Souza 
,
Cássia Cristina Alves Gonçalves,
Luiza Mendonça Higa,
Liane de Jesus Ribeiro,
Vinicius Wakoff Pereira Fonseca
and other authors.
,
Cássia Cristina Alves Gonçalves,
Luiza Mendonça Higa,
Liane de Jesus Ribeiro,
Vinicius Wakoff Pereira Fonseca
and other authors.
This paper is made freely available by the publisher.
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Abstract
In this study, we evaluated mildly symptomatic immunocompetent patients with long-lasting positive rRT-PCR results for SARS-CoV-2. Infectious viruses were successfully isolated in cell cultures from nasopharynx samples obtained 14 days or longer after symptom onset.