25-Hydroxycholesterol Inhibits Kaposi’s Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses
Journal article published in 2021 by
Anna K. P. Serquiña 
,
Takanobu Tagawa ,
Daniel Oh,
Guruswamy Mahesh,
Joseph M. Ziegelbauer
,
Takanobu Tagawa ,
Daniel Oh,
Guruswamy Mahesh,
Joseph M. Ziegelbauer
This paper is made freely available by the publisher.
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Abstract
A cholesterol derivative, 25-hydroxycholesterol (25HC), has been demonstrated to inhibit infections from widely different bacteria and viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, its mechanism of activity is still not fully understood.