Published in
American Association for the Advancement of Science, Science Advances, 48(7), 2021
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Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Journal article published in 2021 by
Luise Linsenmeier 
,
Behnam Mohammadi ,
Mohsin Shafiq ,
Karl Frontzek ,
Julia Bär,
Amulya N. Shrivastava ,
Markus Damme,
Feizhi Song,
Alexander Schwarz ,
Stefano Da Vela ,
Tania Massignan ,
Sebastian Jung ,
Angela Correia,
Matthias Schmitz ,
Berta Puig
and other authors.
,
Behnam Mohammadi ,
Mohsin Shafiq ,
Karl Frontzek ,
Julia Bär,
Amulya N. Shrivastava ,
Markus Damme,
Feizhi Song,
Alexander Schwarz ,
Stefano Da Vela ,
Tania Massignan ,
Sebastian Jung ,
Angela Correia,
Matthias Schmitz ,
Berta Puig
and other authors.
This paper is made freely available by the publisher.
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Abstract
Ligand-stimulated enzymatic release or cellular degradation of PrP may interfere with neurodegeneration-associated toxicity.