Published in
American Society for Microbiology, Microbiology Spectrum, 3(9), 2021
DOI: 10.1128/spectrum.01736-21
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Bacteriophage Therapy for the Prevention and Treatment of Fracture-Related Infection Caused by Staphylococcus aureus: a Preclinical Study
Journal article published in 2021 by
Jolien Onsea 
,
Virginia Post,
Tim Buchholz,
Hella Schwegler,
Stephan Zeiter ,
Jeroen Wagemans ,
Jean-Paul Pirnay ,
Maya Merabishvili,
Matteo D’Este ,
Stijn G. Rotman ,
Andrej Trampuz ,
Michael H. J. Verhofstad ,
William T. Obremskey ,
Rob Lavigne ,
R. Geoff Richards
and other authors.
,
Virginia Post,
Tim Buchholz,
Hella Schwegler,
Stephan Zeiter ,
Jeroen Wagemans ,
Jean-Paul Pirnay ,
Maya Merabishvili,
Matteo D’Este ,
Stijn G. Rotman ,
Andrej Trampuz ,
Michael H. J. Verhofstad ,
William T. Obremskey ,
Rob Lavigne ,
R. Geoff Richards
and other authors.
This paper is made freely available by the publisher.
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Abstract
Because of the growing spread of antimicrobial resistance, the use of alternative prevention and treatment strategies is gaining interest. Although the therapeutic potential of bacteriophages has been demonstrated in a number of case reports and series over the past decade, many unanswered questions remain regarding the optimal application protocol.