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Elsevier, Journal of Vascular Surgery

DOI: 10.1016/j.jvs.2014.09.035

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A successful experimental model for intimal hyperplasia prevention using a resveratrol-delivering balloon

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Restenosis due to intimal hyperplasia is a major clinical problem that compromises the success of angioplasty and endovascular surgery. Resveratrol (RSV) has demonstrated a beneficial effect on restenosis from angioplasty. Unfortunately, the physicochemical characteristics of RSV reduce the practicality of its immediate clinical application. This work proposes an experimental model aiming to setup an intravessel, elutable, RSV-containing compound.