Oil Fly Ash and Vanadium Diminish Nramp-2mrna and Protein Expression in Human Bronchial Epithelial Cells
Published in 2005 by
A. Ghio,
W. Wang,
L. Dailey,
J. Carter,
J. Stonehuerner,
M. Garrick,
Claude Pintadosi,
Funmei Yang
Abstract
The capacity of Nramp2 to transport iron and its ubiquitous expression make it a likely candidate for transferrin-independent uptake of iron in peripheral tissues. Airway epithelial cells increase both mRNA and expression of that isoform of Nramp-2 without an iron response element (-IRE) following exposure to iron.