The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis
Journal article published in 2022 by
Camila G. Quinonez 
,
Jae Jin Lee,
Juhyeon Lim,
Mark Odell,
Christopher P. Lawson,
Amararachukwu Anyogu,
Saki Raheem ,
Hyungjin Eoh
,
Jae Jin Lee,
Juhyeon Lim,
Mark Odell,
Christopher P. Lawson,
Amararachukwu Anyogu,
Saki Raheem ,
Hyungjin Eoh
This paper is made freely available by the publisher.
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Abstract
Understanding the mechanisms underlying M. tuberculosis adaptive strategies to achieve drug tolerance is crucial for the identification of new targets and the development of new drugs. Here, we show that acetate medium triggers a drug-tolerant state in M. tuberculosis when challenged with antituberculosis (anti-TB) drugs.