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American Society for Microbiology, Journal of Bacteriology, 2(194), p. 551-552, 2012

DOI: 10.1128/jb.06392-11

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Genome Sequence of the Haloalkaliphilic Methanotrophic Bacterium Methylomicrobium alcaliphilum 20Z

Journal article published in 2011 by Stéphane Vuilleumier, Valentina N. Khmelenina, Françoise Bringel, Alexandr S. Reshetnikov, Aurélie Lajus, Sophie Mangenot, Zoé Rouy, H. J. M. op den Camp, Huub J. M. Op den Camp ORCID, Mike S. M. Jetten, Alan A. Dispirito, Peter Dunfield, Martin G. Klotz, Jeremy D. Semrau, Lisa Y. Stein and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Methylomicrobium strains are widespread in saline environments. Here, we report the complete genome sequence of Methylomicrobium alcaliphilum 20Z, a haloalkaliphilic methanotrophic bacterium, which will provide the basis for detailed characterization of the core pathways of both single-carbon metabolism and responses to osmotic and high-pH stresses. Final assembly of the genome sequence revealed that this bacterium contains a 128-kb plasmid, making M. alcaliphilum 20Z the first methanotrophic bacterium of known genome sequence for which a plasmid has been reported.