Published in
American Society for Microbiology, Microbiology Spectrum, 1(10), 2022
DOI: 10.1128/spectrum.02100-21
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High Mycobacterium tuberculosis Bacillary Loads Detected by Tuberculosis Molecular Bacterial Load Assay in Patient Stool: a Potential Alternative for Nonsputum Diagnosis and Treatment Response Monitoring of Tuberculosis
Journal article published in 2022 by
Emmanuel Musisi 
,
Abdul Sessolo,
Sylvia Kaswabuli,
Josephine Zawedde,
Patrick Byanyima,
Shariifah Kasinga,
Ingvar Sanyu,
Esther Uwimaana,
Stanley Walimbwa,
Joseph Olore,
Willy Ssengooba,
Christine Sekaggya,
Moses L. Joloba,
William Worodria,
Laurence Huang
and other authors.
,
Abdul Sessolo,
Sylvia Kaswabuli,
Josephine Zawedde,
Patrick Byanyima,
Shariifah Kasinga,
Ingvar Sanyu,
Esther Uwimaana,
Stanley Walimbwa,
Joseph Olore,
Willy Ssengooba,
Christine Sekaggya,
Moses L. Joloba,
William Worodria,
Laurence Huang
and other authors.
This paper is made freely available by the publisher.
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Abstract
This paper highlights the value of stool as a sample type for diagnosis of tuberculosis. While other studies have used DNA-based assays like the Xpert MTB/RIF and culture to detect Mycobacterium tuberculosis in stool, this is the first study that has applied TB-MBLA, an RNA-based assay, to quantify TB bacteria in stool.